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Osteoporosis Research and Future Treatments


Osteoporosis is a debilitating ailment that affects millions of people, particularly seniors. As the US population ages, the number of people that suffer from osteoporosis is expected to grow significantly. As a result, hundreds of millions of dollars are being directed to researching treatments, medications and therapies for this disease. Major pharmaceutical companies, bio-engineering companies and even the US Government (through the National Institutes of Health) are working hard to help people with osteoporosis. It is expected that many new treatments will be brought to market over the coming years and some are even being introduced now.

Here are some of the most promising and exciting treatments in the works.

1. Romosozumab
Romosozumab is a monoclonal antibody. This kind of antibody is made by identical immune cells in the body that are all clones of a parent cell. Polyclonal antibodies are made from a number of different immune cells.

Studies are looking at Romosozumab works to stop the reabsorption process, and interferes with glycoprotein sclerostin in the body. The antibody has gone through Phase 1 and 2 trials, and has shown that patients given the antibody saw an increase in their bone density, which is far more than what current medications can do. With this amazing antibody, we could soon start repairing bones and not just slowing down the damage.

2. Echinacoside
Echinacoside is another chemical that is thought to be a potential future treatment for osteoporosis. This is an antioxidant and a plant derivative that is becoming popular in health enthusiast circles.

Scientists in China have begun testing the antioxidants on rats, considering it a potential treatment for thinning bones. Initial tests have shown that the antioxidant is safe, and so fat it seems like there is some efficacy. More work and research needs to be performed, but the scientists have confirmed that the ratio of OPG and RANKL increased in the blood of the rats when they were given the antioxidant, suggesting that it could soon be used to help repair bone mineral density.